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Sample Size: 3,000mL
Cooling: Jacketed
Dimensions: 30cm×25cm×55cm
Weight: 45kg
Min. Sample Size: 800mL
Application: Liposome formulation up to production scale
Max. Pressure: 80 psi-500 psi
Max. Temp.: 80ºC (176ºF)
Power Type: Compressed gas
Nano-membrane: Track-etched membrane
Cleaning: Flush to clean/CIP/SIP
Sterilization: Whole unit autoclavable
Standard Features
Parts
1) Liposome Jacketed Extruder
2) 10 pieces of 100nm membrane
Feed Reservoir: Temperature-controled jacketed cylinder
Inlet Type: 1/4" high pressure coupling
Outlet Type: 1/4" high pressure coupling
Nitrogen Tubing: G5/8" - 14 TPI BSP inlet nitrogen high pressure soft tubing; adaptor with 3/8-inch male NPT and 1/4-inch female flare outlet
Nano Membrane: 100nm track-etched polycarbonate membrane
Compatibility: Some parts are compatible with Lipex in Northern Lipids
Product Material: 316L stainless steel, NBR or FKM
Material Standard: Sanitary grade; compliant with FDA and GMP sanitary standards
Genizer Lipid Extrusion Methods
Liposomes have grown as an important biomedical carrier system. One of the most critical factors influencing the performance of liposome is particle size. High-pressure homogenization, extrusion and sonication are methods for reducing liposome size. The extrusion technique is a reasonably mild and quick procedure among them.
Genizer liposome extrusion line includes jacketed liposome extruders, online extruders and hand driven liposome extruder
Genizer Jacketed Liposome Extruders:
The Genizer Jacketed Liposome Extruder utilizes a nitrogen gas cylinder to force a drug, protein or gene liposome suspension via a track-etched membrane with a predetermined pore size; generally, 5–10 passes are enough to create a sample with consistent liposome size. The Genizer Jacketed Liposome Extruders are designed to produce uniform unilamellar liposomes and lipopolyplexes with minimal dead volume.
Datasheet
